QuantiferonTB is an in vitro laboratory test for the detecting immune responses to tuberculosis infection. It is an indirect test for Mycobacterium tuberculosis and is an alternative to the tuberculin skin test. It is not affected by a previous BCG vaccination.
It is intended for use as a diagnostic aid for latent M. tuberculosis complex infection. Like the skin test it cannot distinguish between latent and active infection and is intended for use in conjunction with risk assessment, radiography and other medical and diagnostic evaluations.
In individuals suspected of having active TB culture remains the gold standard. Routine use in the diagnosis of active TB is discouraged, due to the phenomenon of false negative results in overwhelming infection.
Padmapriya Kandhan 2253 